Synthesis, production, analytics, and quality — owned and operated under one roof. No outsourcing, no handoffs, no blind spots. From raw material to finished product, every step stays in-house.
A-DIREKT is a vertically integrated biotech company. We own every stage of the value chain — from organic synthesis and botanical extraction through GMP pharmaceutical production to final analytical release. No contract manufacturers, no third-party labs, no waiting on external timelines. One facility, one team, complete control over quality and delivery.
Custom synthesis from milligram to multi-kilogram scale. Jacketed reactors, Schlenk lines, low-temperature capability — all in-house. Because we also own the analytical step, every compound ships with HPLC purity data generated on our instruments.
GMP-qualified lines for granulation, tableting, encapsulation, and film coating. Vertical integration means a formulation moves from development through stability studies to commercial batch release without ever leaving our facility.
LC-MS/MS, GC-MS/MS, preparative LC, three HPLC systems, ICP for heavy metals, and a dedicated microbiology suite. Down the hall from synthesis and production — not in another company's building.
Capsules, tablets, sachets, and liquid formulations manufactured at scale. Full EU regulatory compliance including novel food dossiers. Our integrated supply chain takes a concept from prototype to shelf-ready product with no external dependencies.
Functional products formulated around specific bioavailability targets. Because formulation, production, and testing sit under one roof, each batch undergoes full potency and dissolution verification before release.
Emulsion stability, preservative efficacy testing, regulatory documentation, and packaging — handled end-to-end. Vertical integration means the output is a finished product, not a handoff to another vendor.
Ethanol, supercritical CO₂, hydroethanolic — matched to the target compound. Extracts move directly into our analytical lab for profiling and into our production lines for formulation. No intermediaries.
When off-the-shelf hardware doesn't fit, we design and build it ourselves. Custom reactors, extraction systems, and processing skids — another layer of vertical integration that eliminates dependence on equipment suppliers.
Incoming material testing, in-process controls, batch release, ongoing stability — all performed by our own team on our own instruments. Full traceability from raw material intake to final product release.
This visualisation illustrates the binding interaction between a small-molecule ligand and a seven-transmembrane G-protein coupled receptor. The ligand enters through the extracellular vestibule and settles into the orthosteric binding pocket formed by transmembrane helices III, V, VI, and VII.
Understanding receptor-ligand dynamics at this level is central to our synthesis and analytical work — from designing new compounds to verifying binding affinity with LC-MS/MS.
A-DIREKT started with extraction. Each time we outsourced a capability — synthesis, analytics, production — we lost weeks to logistics and visibility into quality. So we brought them all in-house, one by one, until the entire value chain sat under one roof.
Today the chemist who synthesised a compound walks it to the analyst who runs the LC-MS. That is not a convenience — it is the structural advantage of vertical integration.
Every product — pharmaceutical, supplement, cosmetic — passes through our own analytical pipeline before release. No outsourced certificates, no third-party dependencies, no assumptions.
Tandem mass spectrometry. Sub-ppb quantitation for pharmacokinetics, impurity identification, and multi-residue screening.
Triple-quad volatiles. Residual solvents, pesticide residues, environmental contaminants — single-run detection and quantification.
Gram-scale compound isolation from complex mixtures. High purity, high recovery.
Three systems running potency assays, impurity profiling, and dissolution testing in parallel.
ICP-grade elemental analysis. Pb, Cd, Hg, As to ICH Q3D and European Pharmacopoeia limits.
Dedicated clean room. Total aerobic count, yeast and mold, pathogen screening, endotoxin testing.
Blending, granulation, tableting, encapsulation, coating. All IQ/OQ/PQ qualified.
Fast identity confirmation, reaction monitoring, purity screening. The daily tools of synthesis QC.
Gotthardská 25/7
160 00 Praha 6-Bubeneč, Czech Republic
VAT ID: CZ25954946
ID: 25954946